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About Nanoknife

Published on April 29, 2015

Irreversible electroporation (IRE) with the NanoKnife® System is a surgical technique that uses very short but strong electric pulses to destroy cancerous cells using high-voltage direct current that does not injure surrounding non-cancerous cells, blood vessels and other vital structures. It has been in patients since 2008 in the treatment of some types of cancers. One of the largest unmet needs in cancer that IRE has been used is in locally advanced (Stage III) pancreatic cancer.  Recent studies have demonstrated its safety with encouraging improvement in overall survival. There are limitations to the treatment, as well. UofL Physicians - Surgical Oncology is trying to determine if the Nanoknife can be used to safely and effectively treat locally advanced pancreatic cancer.

Dr. Robert Martin, a surgical oncologist at UofL Physicians, explains Irreversible Electroporation (IRE) in the pancreas in this NanoKnife Procedural Best Practice Series video above.

For more information or to learn more about if you are a candidate, call UofL Physicians - Surgical Oncology at 502-583-8303.

To make a referral, call 502-583-8303.

What is IRE?

Information for Possible IRE Patients

Publications about IRE

More Videos

Pancreatic cancer treatment has saved the life of a woman who was given nine months to live. She is now four years out from the procedure and doctors aren't seeing any active disease: See the video.

Case 1: Locally Advanced Pancreatic Cancer with Metal Stent Management

Case 2: Recurrent Cholangiocarnimona Refractory to Chemotherapy

Case 3: Borderline Resectable Pancreatic Cancer Management