Neuro-Oncology

Tumors can develop in the central nervous system (CNS), which includes the brain and spinal cord. Patients with these tumor types are best treated in a multidisciplinary clinic setting. A team of neurosurgeons, neuro-oncologists, radiation oncologists, pathologists, neuro-radiologists and physical medicine and rehabilitation specialists join together to create the UofL Physicians – Neuro-Oncology team and provide expert care in their fields. Every Thursday, our Neuro-Oncology team gathers for Tumor Board to discuss cases and determine best treatment options for the patients. Patients are then updated, as indicated based on the consensus of the Neuro-Oncology department, in order to proceed with the recommended treatment. This is the clinical approach we can provide at UofL Physicians – Neuro-Oncology, within the UofL James Graham Brown Cancer Center's Brain and Spine Tumor Clinic.

Our team has a wealth of experience evaluating and treating patients with primary and secondary tumors of the brain and spinal cord, and we use the latest techniques and modalities to provide the best care for our patients. The UofL Physicians – Neuro-Oncology team is dedicated to the delivery of excellent patient care via an integrated multidisciplinary approach. This philosophy is manifest in our patient-centered, collaborative approach to clinic care, our desire to develop novel treatments to improve patient survival and enhance quality of life. To achieve these goals, we see to improve our understanding of the biological basis of the diseases we treat through cutting-edge research and train future leaders in neuro-oncology. 

In addition to having investigator-initiated and industry-sponsored clinical research trials for primary and metastatic brain cancer, UofL Physicians - Neuro-Oncology is actively involved in clinical research as a member of the Radiation Therapy Oncology Group. As teachers and researchers at the UofL School of Medicine, our physicians are committed to clinical research and applying that in practice for patients to obtain their best chance of quality survival. Our physicians specialize in laser ablation, Cyberknife focused radiosurgery and Optune, a more advanced, non-invasive treatment method used for some newly diagnosed and recurrent gliomas.

To find a member of the UofL Physicians Neuro-Oncology team, click on the Our Physicians tab.

 

Each patient is discussed individually in our team’s weekly Neuro-Oncology conference. All treatment plans are developed at this multidisciplinary conference. Our goal is to use the most effective and minimally invasive treatment modality available for each patient and their specific case.  

  • Anaplastic astrocytoma
  • Anaplastic oligodendroglioma
  • Astrocytoma
  • Brain metastases
  • Central neurocytoma
  • Colloid cyst
  • Dysembryoplastic Neuroepithelial Tumor
  • Ependymoma
  • Ganglioglioma
  • Glioblastoma multiforme
  • Glioma
  • Meningioma
  • Oligodendroglioma
  • Pleomorphic xanthoastrocytoma
  • Pinealoblastoma

Each patient is discussed individually in our team’s weekly Neuro-Oncology conference. All treatment plans are developed at this multidisciplinary conference. Our goal is to use the most effective and minimally invasive treatment modality available for each patient and their specific case.  

Surgical

  • Biopsy for diagnosis-- open or endoscopic/stereotactic
  • Open and awake craniotomy for tumor resection for tumors in eloquent, or near-eloquent, areas
  • Surgical resection
  • Laser ablation for recurrence or difficult to ACCESS locations—the only facility to offer this in the region

Radiation

  • Radiotherapy
  • Cyberknife focused radiation-- the only facility to offer this in the region

Medical

  • Chemotherapy, both conventional and experimental options
  • Optune
    • Formerly the NovoTTF™-100A System, Optune is approved for treatment of recurrent Glioblastoma, the most common and aggressive type of malignant brain tumor in adults. Optune is a portable, non-invasive anti-mitotic device designed for continuous use throughout the day by the patient.
    • Studies show the device slows tumor growth by inhibiting division of cancer cells. And it is a more advanced, non-invasive treatment than chemotherapy.

Rehabilitation

  • Frazier Rehabilitation Center
  • Dr. Megan Nelson is the Neuro-Oncology Department's Cancer Rehabilitation specialist, dedicated to providing personalized care to patients and families in an innovative way using the most advanced health care techniques.

Physicians in this practice may not see patients at all locations listed below. For details, please call the appointment line for the location you are interested in visiting.

Offices and Clinics

  • UofL Physicians - Neuro-Oncology at James Graham Brown Cancer Center
    529 S. Jackson St.
    Louisville, Kentucky 40202
    502-562-HOPE (4673)
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  • UofL Physicians - Neuro-Oncology at Frazier Rehab Institute
    220 Abraham Flexner
    12th Floor
    Louisville , Kentucky 40202
    502-899-3623
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  • UofL Physicians - Neuro-Oncology at Ambulatory Care Building
    550 S. Jackson St.
    1st Floor
    Louisville, Kentucky 40202
    502-562-6501
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Hospital Affiliations

  • University of Louisville Hospital
  • James Graham Brown Cancer Center
  • Jewish Hospital
 
UofL Physicians Tumor Board. Dr. Norm Lehman is included as a member of the Tumor Board. Dr. Neimat and Dr. Silverman are not pictured.

A team of neuro-oncologists, neurologists, neurosurgeons, radiation oncologists and physical medicine and rehabilitation specialists join together to create UofL Physicians - Neuro-Oncology and provide expert care in their fields.

Next Steps

For more information or to make an appointment,
call 502-588-6000